During the 13th century in Yeke Mongol Ulus, which was once the largest empire in history, Fatima from Persia arrived at the palace of the Mongols. Fatima was known for her medical expertise and scientific knowledge, which had been refined beyond any previous standards in her homeland. Fatima sought a platform where she could apply her knowledge, which led her to the palace of the Mongols under the guidance of Töregene, the sixth wife of Ögedei, the second Great Khan-a powerful woman with complex emotions about the empire's direction. Fatima and Töregene formed the axis around which the palace politics and eventually the entire world would revolve.