The Sagimiya family is afflicted with a curse that causes its members to become sexually aroused when in the presence of someone from the same bloodline. Despite being repulsed by this phenomenon, Misaki and her twin brother, Shun, have vowed to resist their genetic calling. However, Shun's self-control falters, leading him to seek release with their older sister, Kagu. Upon discovering this, Misaki also succumbs to temptation and seeks out Shun as well.