In 71st year of True Era, humans have expanded into space and established independent galactic colonies. Earth is divided between two superpowers- Atlantic Rim United States (ARUS) and Dorssia Military Pact Federation (Dorssia), who frequently wage war against each other on earth and beyond. A third faction comprising of Japan and Islands of Oceanian Republic (JIOR) live peacefully and prosper economically, maintaining neutrality with their militant neighbors. The story begins in an outer space JIOR colony where 17-year-old Haruto Tokishima's peaceful life is disrupted when a sudden Dorssian fleet attacks the neutral colony to seize Valvraves- powerful but rumored mechanized weapons hidden deep within Haruto's school, Sakimori Academy. In chaos, Haruto discovers one of the targeted Valvrave and with his friends' lives at stake, he enters into a contract with it by sacrificing his humanity in exchange for its power to initiate a revolution against Dorssia to liberate the world. He is assisted by L-elf- an enigmatic Dorssian agent and gifted strategist.
Kakumeiki Valvrave was the first Anime to receive a Simulcast in Germany.