Bannou Bunka Nekomusume (1998)  

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The anime series "Nuku Nukus" follows the adventures and mishaps of its protagonist, Nuku Nuku, in high school as well as her relationships with other students. The main plot revolves around Mishima Industries' plan to take over the world through their products. Standing against this scheme are Kyuusaku Natsume and his android companion, Nuku Nuku. Nuku Nuku's classmates are all unique individuals with distinct personalities. Futaba is a controlling authority figure who cannot let go of her power in school. Chieko Shirakaba is the rich snob with two loyal followers. There's also a bookworm, a mystic, a scientist, and a pop singer, each true to their descriptions. The eccentricities of these characters add humor to the series.