Relena is a privileged daughter of an Earth Alliance minister who attends a prestigious private school. She longs for more excitement in her life and finds it when she meets Heero Yuy, a Gundam pilot. Her father reveals her true identity as the daughter of King Peacecraft of the Sanc Kingdom, who was taken away during an attack by Alliance forces. Relena decides to follow in her parent's footsteps and become an advocate for peace and nonviolence in a world that is becoming increasingly chaotic. In Frozen Teardrop.
Relena was stored away in a capsule with the codename "Little Prince." She was frozen on her way to Mars from Earth due to unknown troubles. The goal of Operation Mythos is to assassinate Relena Peacecraft, however the reason is currently unknown. Unfrozen after the assassination of "Milliardo Peacecraft", she takes his place as the second President of the Mars Federation, appearing with a mask identical to that which her brother, Zechs Merquise, once wore.