A French Jew who served as a colonel in the French army and collaborated with the Qing-Bang. Although he was familiar with Sonkaken, he preferred to use conventional weapons like guns and swords in combat. He had a sister named Sophie, who experienced trauma due to her escape from Nazi Germany. After regaining her memory through Kenshiros acupressure, she was assassinated by Zhang Tai Yan. De Guise eventually died after being fatally wounded by Liú Fēi-Yàn in a duel over his unworthiness to care for Erika. Before dying, he watched as Kenshiro and friends staged a vision of a prosperous Shanghai where Jews could seek refuge. Believing that this vision would become reality, De Guise passed away peacefully.