Reiko Shiratori is a beautiful and wealthy high school student who often uses her catchphrase "Do you think someone like me would do something like this?" to dismiss suitors. One day, Tetsuya confessed his love to her, but she rejected him as usual. Despite being heartbroken, Tetsuya walked away without knowing that Reiko actually loved him. After graduating from high school, Reiko followed Tetsuya to the same university he attended and rented an apartment near his place. They studied in the same building, pretending it was a coincidence. However, Tetsuya's persistence eventually paid off when he found out about Reiko's true feelings through one-shots such as "Watashi no Otoko ni Te wo Dasuna!!!", "1980-en no Marilyn", "Goippatsu Dou desu ka?", and "Antagata Busu sa♡, Junai RIsshinben".
Shiratori Reiko de Gozaimasu has been adapted to three live-action television series, airing in 1989, 1993, and 2016, and to live-action theatrical films released in 1995 and 2016.