On her first day at Itan Private High School, Shouko Komis quickly gained popularity due to her long black hair and graceful appearance. However, despite this, she struggles with effective communication. Meanwhile, Hitohito Tadano is an average high school student who follows the motto of "reading situations and avoiding trouble." When he sits next to Shouko, he becomes the target of dislike from his classmates. One day, while knocked out by accident, Hitohito wakes up to the sound of Shoukos "meow". He lies about hearing nothing, causing Shouko to flee. Later, Hitohito realizes that Shouko has difficulty communicating with others and has never made a friend. Determined to help her overcome this challenge, he sets a goal for her to make one hundred friends.
Komi-san wa, Comyushou desu. has been published in English as Komi Cant Communicate by VIZ Media under the Shonen Sunday imprint since June 19, 2019. The series has also been published in German by Tokyopop since July 1, 2020, and in Italian by JPOP since September 2020.