After finishing middle school, Rentarou expresses his feelings for the girl he loves. Unfortunately, he is rejected again, making it his 100th rejection in a row. Feeling downhearted, he visits a shrine for matchmaking and prays for a girlfriend in high school. To his surprise, the shrine's god appears and promises that he will meet one hundred soulmates in high school. Although initially skeptical, Rentarou is convinced of the god's words when two of his soulmates declare their feelings for him on the same day they meet him. However, there is one condition that the god overlooked: if any of his soulmates fail to establish a relationship with him, they will die. Now faced with a life-or-death situation, Rentarou decides to date all of his soulmates. With a heart big enough to share among one hundred girlfriends, he makes the most of his unexpected high school experience, with his family growing ever larger!
Kimi no Koto ga Daidaidaidaidaisuki na 100-nin no Kanojo has been published in English as The 100 Girlfriends Who Really, Really, Really, Really, Really Love You by Seven Seas Entertainment under the Ghost Ship imprint since February 22, 2022.