In Japan, a plague-like rust has spread throughout the land. The tale follows the quest of Bisco Akaboshi, the strongest mushroom hunter, along with young doctor Milo Nekoyanagi as they search for the legendary medicinal mushroom "Sabikui". This mythical fungus is said to be the cure for the rust that has afflicted their homeland.
Sabikui Bisco won Silver Prize in the 2017 Dengeki Novel Prize, and placed first in the Kono Light Novel ga Sugoi! ranking in the best light novel category in 2019.