Subete ga F ni Naru  

Professor Saikawa and Moe Nishinosono travel to an island where Professor Shiki Magata has his private laboratory. They are intrigued by the murder of his parents and manage to gain entry to the lab. Suddenly, a corpse dressed in Magatas clothing is violently ejected from her quarters. It's clear that she was murdered, and this is only the beginning...

Subete ga F ni Naru is based on the Hiroshi Moris 1996 mystery novel of the same title, which is the first book in his S&M series. It is the second manga adaptation of the novel.