Serena Nekozuka is a diligent third-year high school student striving to earn a scholarship. Despite her attractive appearance, she doesn't adhere to her school's dress code. Reiko Tachibana, a member of the disciplinary committee, frequently reminds her of this issue. Furthermore, Reiko consistently outperforms Serina in academics and sports. One day, while observing Reiko after school, Serina discovers her meeting with an unknown woman at a love hotel. What transpires between these two women now that they have kept this secret?
Spica wo Tsukamaete has been licensed in English as Chasing Spica by Seven Seas Entertainment.