Momoko Sakura is an elementary school student who enjoys idol Momoe Yamaguchi and reading mangas. She's often referred to as "Chibi Maruko-chan" because of her youthful age and small stature. Along with her parents, grandparents, and elder sister, she resides in a quaint town. At school, she has numerous friends whom she studies and plays with daily, including her closest companion, Tama-chan; the student council members, Maruo-kun and Migiwa-san; and the B-class trio consisting of little master Hanawa-kun, Hamaji-Bu Taro, and Sekiguchi-kun. This anime portrays a lighthearted and enjoyable depiction of everyday life.