Noin was once a friend of Zechs from their time at Lake Victoria Military Academy. After graduation, she became part of the academy's staff and trained new recruits for space combat. Despite being an accomplished mobile suit pilot herself, Noin does not enjoy fighting and often tries to resolve conflicts peacefully through her influence with OZ leader Treize Khushrenada. She is fiercely loyal to Zechs and his younger sister Relena, eventually becoming a Special Guard of the Sanc Kingdom in order to safeguard them. In Frozen Teardrop.
When he is assassinated by an anti-Mars Federation rebel group, Noin and her children attend the funeral- notably not shedding any tears for the dead "Milliardo", with Zechs standing behind them.
At an unknown date, Milliardo and Noin marry and have twins, Naina and Milou. While Zechs leaves with Naina to travel Mars under a new alias, Noin stays behind with Milou. Her elder brother, Nix-Deuf Noinheim, is the President of a large Corporation and takes Milliardos name as his own alias, under which he becomes the first President of Mars.